In collaboration

Diagnosis and Management of Myocarditis in Children: A Scientific Statement From the American Heart Association.

Law YM, Lal AK, Chen S, Čiháková D, Cooper LT Jr, Deshpande S, Godown J, Grosse-Wortmann L, Robinson JD, Towbin JA; American Heart Association Pediatric Heart Failure and Transplantation Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young and Stroke Council.Circulation. 2021 Aug 10;144(6):e123-e135. doi: 10.1161/CIR.0000000000001001. Epub 2021 Jul 7.

Natriuretic Peptide Levels and Clinical Outcomes Among Patients Hospitalized With Coronavirus Disease 2019 Infection.

Aslam MI, Minhas A, Ghorbani A, Shade JK, Jani V, Hsu S, Sharma K, Cihakova D, Hays AG, Gilotra NA.Crit Care Explor. 2021 Jul 16;3(7):e0498. doi: 10.1097/CCE.0000000000000498. eCollection 2021 Jul.PMID: 34291225

Transcriptomic Analysis of Inflammatory Cardiomyopathy Identifies Molecular Signatures of Disease and Informs in silico Prediction of a Network-Based Rationale for Therapy.

Singh K, Fang H, Davies G, Wright B, Lockstone H, Williams RO, Ciháková D, Knight JC, Bhattacharya S.Front Immunol. 2021 Mar 5;12:640837. doi: 10.3389/fimmu.2021.640837. eCollection 2021.PMID: 33746983 Free PMC article.

Complete recovery of fulminant cytotoxic CD8 T-cell-mediated myocarditis after ECMELLA unloading and immunosuppression.

Jurcova I, Rocek J, Bracamonte-Baran W, Zelizko M, Netuka I, Maluskova J, Kautzner J, Cihakova D, Melenovsky V, Maly J.ESC Heart Fail. 2020 Aug;7(4):1976-1981. doi: 10.1002/ehf2.12697. Epub 2020 Jun 2.PMID: 32485066

The Effects of a Gluten-Free Diet on Immune Markers and Kynurenic Acid Pathway Metabolites in Patients With Schizophrenia Positive for Antigliadin Antibodies Immunoglobulin G.

Friendshuh CR, Pocivavsek A, Demyonovich H, Rodriguez KM, Cihakova D, Talor MV, Richardson CM, Vyas G, Adams HA, Baratta AB, Fasano A, Cascella N, Feldman S, Liu F, Sayer M, Powell MM, Wehring HJ, Buchanan RW, Carpenter WT Jr, Eaton WW, Kelly DL.J Clin Psychopharmacol. 2020 May/Jun;40(3):317-319. doi: 10.1097/JCP.0000000000001197.PMID: 32332475

Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans.

Chung L, Maestas DR Jr, Lebid A, Mageau A, Rosson GD, Wu X, Wolf MT, Tam AJ, Vanderzee I, Wang X, Andorko JI, Zhang H, Narain R, Sadtler K, Fan H, Čiháková D, Le Saux CJ, Housseau F, Pardoll DM, Elisseeff JH.Sci Transl Med. 2020 Apr 15;12(539):eaax3799. doi: 10.1126/scitranslmed.aax3799.PMID: 32295900

Racial Differences in S100b Levels in Persons with Schizophrenia

Jessica M. Gannon ,Deanna L. Kelly, Abigail Besch, Tanu Thakur,Neil Khurana, Michael R. Shurin, Galina V. Shurin, Jaspreet S. Brar,
Daniela Cihakova, Monica V. Talor , K. N. Roy Chengappa

Psychiatric Quarterly (2020) 91:137–145 https://doi.org/10.1007/s11126-019-09687-4

Randomized controlled trial of a gluten-free diet in patients with schizophrenia positive for antigliadin antibodies (AGA IgG): a pilot feasibility study

Kelly DL, Demyanovich HK, Rodriguez KM, Ciháková D, Talor MV, McMahon RP, Richardson CM, Vyas G, Adams HA, August SM, Fasano A, Cascella NG, Feldman SM, Liu F, Sayer MA, Powell MM, Wehring HJ, Buchanan RW, Gold JM, Carpenter WT, Eaton WW.

J Psychiatry Neurosci. 2019 Mar 27;44(3):1-9. [Epub ahead of print]

PMID:30938127

The recruitment of extra-intestinal cells to the injured mucosa promotes healing in radiation enteritis and chemical colitis in a mouse parabiosis model.

Sung J, Sodhi CP, Voltaggio L, Hou X, Jia H, Zhou Q, Čiháková D, Hackam DJ.

Mucosal Immunol. 2019 Jan 7. doi: 10.1038/s41385-018-0123-3. [Epub ahead of print] PMID:30617302

Antigliadin Antibodies (AGA IgG) Are Related toNeurochemistry in Schizophrenia .

Laura M. Rowland, Haley K. Demyanovich, S. Andrea Wijtenburg, William W. Eaton, Katrina Rodriguez, Frank Gaston, Daniela Cihakova, Monica V. Talor, Fang Liu, Robert R. McMahon, L. Elliot Hong and Deanna L. Kelly . Front. Psychiatry, 19 June 2017 | https://doi.org/10.3389/fpsyt.2017.00104

Dr. Daniela Cihakova highlights autoimmune disease in the Reader’s Digest! April 2017

http://www.rd.com/…/con…/millennials-and-autoimmune-disease/

A Subset of Men with Age-Related Decline in Testosterone have Gonadotroph Autoantibodies.

Ricciuti A, Travison TG, Di Dalmazi G, Talor MV, DeVincentiis L, Manley RW, Bhasin S, Caturegli P, Basaria S. J Clin Endocrinol Metab. 2016 Apr;101(4):1535-41. doi: 10.1210/jc.2016-1016. Epub 2016 Mar 10.

Cardiac antibody production to self-antigens in children and adolescents during and following the correction of severe diabetic ketoacidosis.

Hoffman WH, Sharma M, Čiháková D, Talor MV, Rose NR, Mohanakumar T, Passmore GG. Autoimmunity. 2016 May;49(3):188-96. doi: 10.3109/08916934.2015.1134509. Epub 2016 Feb 25.

Cannabidiol limits Tcell-mediated chronic autoimmune myocarditis: implications to autoimmune disorders and organ transplantation.

Lee WS, Erdelyi K, Matyas C, Mukhopadhyay P, Varga ZV, Liaudet L, Haskó G, Čiháková D, Mechoulam R, Pacher P. Mol Med. 2016 Jan 8. doi: 10.2119/molmed.2016.00007. [Epub ahead of print]

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes.

Hobbs RP, DePianto DJ, Jacob JT, Han MC, Chung BM, Batazzi AS, Poll BG, Guo Y, Han J, Ong S, Zheng W, Taube JM, Čiháková D, Wan F,Coulombe PA. Nat Genet. 2015 Aug;47(8):933-8. doi: 10.1038/ng.3355. Epub 2015 Jul 13.

Transcriptomic profiles of aging in purified human immune cells.

Reynolds LM, Ding J, Taylor JR, Lohman K, Soranzo N, de la Fuente A, Liu TF, Johnson C, Barr RG, Register TC, Donohue KM, Talor MV, Čiháková D, Gu C, Divers J, Siscovick D, Burke G, Post W, Shea S, Jacobs DR Jr, Hoeschele I, McCall CE, Kritchevsky SB, Herrington D, Tracy RP, Liu Y. BMC Genomics. 2015 Apr 22;16:333. doi: 10.1186/s12864-015-1522-4.

Increased Systemic Th17 Cytokines Are Associated with Diastolic Dysfunction in Children and Adolescents with Diabetic Ketoacidosis

Hoffman WH, Passmore GG, Hannon DW, Talor MV, Fox P, Brailer C, Haislip D, Keel C, Harris G, Rose NR, Fiordalisi I, Čiháková D. PLoS One. 2013 Aug 27;8(8):e71905. doi: 10.1371/journal.pone.0071905. eCollection 2013.

IL-33 independently induces eosinophilic pericarditis and cardiac dilation: ST2 improves cardiac function.

Abston ED, Barin JG, Čiháková D, Bucek A, Coronado MJ, Brandt JE, Bedja D, Kim JB, Georgakopoulos D, Gabrielson KL, Mitzner W, Fairweather D. Circ Heart Fail. 2012 May 1;5(3):366-75. doi: 10.1161/CIRCHEARTFAILURE.111.963769. Epub 2012 Mar 27.

Alternatively activated macrophages in infection and autoimmunity.

Fairweather D, Ciháková D. J Autoimmun. 2009 Nov-Dec;33(3-4):222-30. doi: 10.1016/j.jaut.2009.09.012. Epub 2009 Oct 12.

Sjögren syndrome: advances in the pathogenesis from animal models.

Chiorini JA, Čiháková D, Ouellette CE, Caturegli P. J Autoimmun. 2009 Nov-Dec;33(3-4):190-6. doi: 10.1016/j.jaut.2009.09.009. Epub 2009 Oct 2.

Sex differences in a murine model of Sjögren’s syndrome.

Ciháková D, Talor MV, Barin JG, Baldeviano GC, Fairweather D, Rose NR, Burek CL. Ann N Y Acad Sci. 2009 Sep;1173:378-83. doi: 10.1111/j.1749-6632.2009.04760.x.

Pathogenesis of myocarditis and dilated cardiomyopathy.

Ciháková D, Rose NR. Adv Immunol. 2008;99:95-114. doi: 10.1016/S0065-2776(08)00604-4.

L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart.

Ciháková D, Barin JG, Baldeviano GC, Kimura M, Talor MV, Zimmerman DH, Talor E, Rose NR. Int Immunopharmacol. 2008 May;8(5):624-33. doi: 10.1016/j.intimp.2008.01.004. Epub 2008 Jan 29.

Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation.

Ciháková D, Barin JG, Afanasyeva M, Kimura M, Fairweather D, Berg M, Talor MV, Baldeviano GC, Frisancho S, Gabrielson K, Bedja D, Rose NR. Am J Pathol. 2008 May;172(5):1195-208. doi: 10.2353/ajpath.2008.070207. Epub 2008 Apr 10.

Cutting edge: cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease.

Frisancho-Kiss S, Davis SE, Nyland JF, Frisancho JA, Ciháková D, Barrett MA, Rose NR, Fairweather D. J Immunol. 2007 Jun 1;178(11):6710-4.

Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity.

Frisancho-Kiss S, Nyland JF, Davis SE, Barrett MA, Gatewood SJ, Njoku DB, Ciháková D, Silbergeld EK, Rose NR, Fairweather D. J Immunol. 2006 Jun 1;176(11):6411-5.

Animal models for autoimmune myocarditis and autoimmune thyroiditis.

Ciháková D, Sharma RB, Fairweather D, Afanasyeva M, Rose NR. Methods Mol Med. 2004;102:175-93.

Cardiomyopathies.

Rose NR, Ciháková D. Autoimmunity. 2004 Jun;37(4):347-50.

Novel AIRE mutations and P450 cytochrome autoantibodies in Central and Eastern European patients with APECED.

Ciháková D, Trebusak K, Heino M, Fadeyev V, Tiulpakov A, Battelino T, Tar A, Halász Z, Blümel P, Tawfik S, Krohn K, Lebl J, Peterson P. Hum Mutat. 2001 Sep;18(3):225-32.

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