Recent Publications:

  1. Chunfa Jie, R Ahmed, ARA Hamad. Expression of unique gene signature distinguishes TCRαβ+/BCR+ dual expressers from CD3+CD14+ doublets. Cytometry Part A 101 (4), 283-289 –published April 2022. doi: 10.1002/cyto.a.24542
  2. Rizwan Ahmed, Kusuma Ananth, Zahra Omidian, Neha Majety, Hao Zhang, Abdel Rahim A Hamad. Detection, sorting, and immortalization of dual expresser lymphocytes from human peripheral blood samples. STAR protocols 2 (4), 100925- December 2021. doi: 10.1016/j.xpro.2021.100925.
  3. Jaiswal AK, Sadasivam M, Aja S, Hamad ARA. Lack of Syndecan-1 produces significant alterations in whole-body composition, metabolism and glucose homeostasis in mice. World J Diabetes. 2020 Apr 15;11(4):126-136. doi: 10.4239/wjd.v11.i4.126.
  4. Gong J, Noel S, Hsu J, Bush EL, Arend LJ, Sadasivam M, Lee SA, Kurzhagen JT, Hamad ARA, Rabb H. TCR+CD4-CD8- (double negative) T cells protect from cisplatin-induced renal epithelial cell apoptosis and acute kidney injury. Am J Physiol Renal Physiol. 2020 Apr 13;. doi: 10.1152/ajprenal.00033.2020.
  5. Gharaie Fathabad S, Kurzhagen JT, Sadasivam M, Noel S, Bush E, Hamad ARA, Rabb H. T Lymphocytes in Acute Kidney Injury and Repair. Semin Nephrol. 2020 Mar;40(2):114-125. doi: 10.1016/j.semnephrol.2020.01.003. Review
  6. Lee SA, Noel S, Kurzhagen JT, Sadasivam M, Pierorazio PM, Arend LJ, Hamad AR, Rabb H. CD4+ T Cell-Derived NGAL Modifies the Outcome of Ischemic Acute Kidney Injury. J Immunol. 2020 Feb 1;204(3):586-595. doi: 10.4049/jimmunol.1900677.
  7. Sadasivam M, Noel S, Rabb H, Hamad ARA. Renal double negative T cells: increasing importance in health and disease. Ann Transl Med. 2020 Feb;8(4):143. doi: 10.21037/atm.2019.11.51.
  8. Giwa AM, Ahmed R, Omidian Z, Majety N, Karakus KE, Omer SM, Donner T, Hamad ARA. Current understandings of the pathogenesis of type 1 diabetes: Genetics to environment. World J Diabetes. 2020 Jan 15;11(1):13-25. doi: 10.4239/wjd.v11.i1.13. Review
  9. Hsu J, Krishnan A, Lee SA, Dodd-O JM, Kim BS, Illei P, Yarnoff K, Hamad AA, Rabb H, Bush EL. CD3+CD4-CD8- Double-negative αβ T cells attenuate lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2019 Nov 2;. doi: 10.1016/j.jtcvs.2019.09.188.
  10. Hamad ARA, Sadasivam M, Rabb H. Hybrid lipids, peptides, and lymphocytes: new era in type 1 diabetes research. J Clin Invest. 2019 Aug 5;130:3527-3529. doi: 10.1172/JCI130313.
  11. Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell DR, Lee S, Zhang H, Michels A, Desiderio S, Sadegh-Nasseri S, Rabb H, Gritsch S, Suva ML, Cahan P, Zhou R, Jie C, Donner T, Hamad ARA. A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen. 2019 May 30;177(6):1583-1599.e16. doi: 10.1016/j.cell.2019.05.007.
  12. Omidian Z, Ahmed R, Giwa A, Donner T, Hamad ARA. IL-17 and limits of success. Cell Immunol. 2019 May;339:33-40. doi: 10.1016/j.cellimm.2018.09.001. Epub 2018 Sep 17. Review.
  13. Sadasivam M, Noel S, Lee SA, Gong J, Allaf ME, Pierorazio P, Rabb H, Hamad ARA. Activation and Proliferation of PD-1+ Kidney Double-Negative T Cells Is Dependent on Nonclassical MHC Proteins and IL-2. J Am Soc Nephrol. 2019 Feb;30(2):277-292. doi: 10.1681/ASN.2018080815.
  14. Gong J, Noel S, Pluznick JL, Hamad ARA, Rabb H. Gut Microbiota-Kidney Cross-Talk in Acute Kidney Injury. Semin Nephrol. 2019 Jan;39(1):107-116. doi: 10.1016/j.semnephrol.2018.10.009. Review.

Complete List of Published Work in MyBibliography

Additional recent publications of importance to the field

  1. Xiao, X., Mohamood, A.S., Uddin, S., Gutfreund, R., Nakata, S., Marshall, A., Kimura, H., Caturegli, P., Womer, K.L., Huang, Y., J. Schneck, Hideo Yagita and Abdel Rahim Hamad. Inhibition of Fas ligand in NOD mice unmasks a protective role for IL-10 against insulitis development. Am J Pathol. 2011;179:752-32. PMID 21718680
  2. Immunotherapy for Type 1 Diabetes: Necessity, Challenges and Unconventional Opportunities. Type 1 Diabetes / Book 1″, ISBN 978-953-307. 2011.
  3. Mohamood AS, Trujillo CJ, Zheng D, Jie C, Murillo FM, Schneck JP and A. R. Hamad. Gld mutation of Fas ligand increases the frequency and upregulates cell survival genes in CD25+CD4+ Treg Cells. Int Immunol. 2006; 18:1265. PMID 16769751
  4. Mohamood A., M Guler, X. Zuoxiang, D. Zheng, Y. Wang, H. Yagita, J Schneck and A. R. Hamad. 2007. Protection from autoimmune diabetes and T cell lymphoproliferation-induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically. Am J Pathol 171:97. PMID 17591957