Faculty

William Clarke, Ph.D.

Dr. William Clarke received his Ph.D. in Analytical Chemistry from the University of Nebraska in Lincoln in 2000, followed by a post-doctoral fellowship in Clinical Chemistry at the Johns Hopkins School of Medicine, ending in 2002. In addition, he received an MBA focused on medical services management from the Carey School of Business at Johns Hopkins in 2007. Following his post-doctoral fellowship, he remained at Johns Hopkins, where he is an Associate Professor in the Department of Pathology, as well as the director of both Point-of-Care Testing and Clinical Toxicology for the hospital. Dr. Clarke is board certified in Clinical Chemistry by the American Board of Clinical Chemistry, and is a Fellow of the National Academy of Clinical Biochemistry. His research interests include clinical mass spectrometry, method development and evaluation for therapeutic drug monitoring, clinical toxicology, point-of-care testing, and development/validation of biomarkers for use in drug management. Dr. Clarke has published as author or co-author over 80 peer-reviewed manuscripts or book chapters. View Dr. Clarke’s Full Profile >>

Daniel Chan, Ph.D.

Dr. Daniel Chan is the Director of The Center for Biomarker Discovery and Translation and Professor of Pathology, Oncology, Radiology and Urology at the Johns Hopkins University. He is also the Director of Clinical Chemistry Division and the Co-Director of Pathology Core Laboratory at the Johns Hopkins Hospital, Baltimore, Maryland, USA. Dr. Chan is a diplomat of the American Board of Clinical Chemistry (ABCC) and a fellow of the National Academy of Clinical Biochemistry (NACB). He is an internationally recognized expert in cancer biomarkers, clinical proteomics and molecular diagnostics. He has written 5 books, 40 book chapters and over 275 scientific articles. He has been funded by the NCI as the Principal investigator of the CPTAC (Cancer Proteomic Tumor Analysis Consortium) and the Biomarker Reference Lab for the EDRN (Early Detection Research Network) as well as the investigator of the Prostate Spore program. During the last 20 years, Dr. Chan has trained over 20 clinical chemistry fellows at Johns Hopkins. Many of these scientists have become leaders in Clinical Chemistry. He has given over one hundred invited lectures, both within and outside of US. Dr. Chan received more than 20 awards for his outstanding contributions to science, education and leadership from professional societies. He served as the Chair of the Proteomics Division (a founder) of the American Association for Clinical Chemistry (AACC), Board of Directors of NACB and as the President of the National Registry in Clinical Chemistry (NRCC). Currently, he is the President of the International Society of Enzymology (ISE) and on the Board of Directors (a founder) of the US Human Proteome Organization (HUPO). He is the Editor-in-Chief of the journal Clinical Proteomics. View Dr. Chan’s Full Profile >>

Lori Sokoll, Ph.D.

Dr. Lori Sokoll is a Professor of Pathology in the Johns Hopkins University School of Medicine and has secondary appointments in Oncology and Urology. She is the Associate Director of the Clinical Chemistry Division and Director of the Special Chemistry Laboratory in The Johns Hopkins Hospital. Dr. Sokoll received her A.B. degree from Cornell University. She has a Master of Clinical Chemistry degree from Hahnemann University and received a Ph.D. in Human Nutrition Sciences from Tufts University. She completed a two-year ComACC-accredited Postdoctoral Fellowship in Clinical Chemistry at the Johns Hopkins Medical Institutions. Her research focuses on the evaluation and clinical applications of cancer biomarkers. She is a co-investigator for the NCI sponsored EDRN and CPTAC programs. View Dr. Sokoll’s Full Profile >>

Mark Marzinke, Ph.D.

Dr. Mark Marzinke is a Professor of Pathology at the Johns Hopkins University School of Medicine. He received his PhD in Biochemistry from the University of Wisconsin-Madison and completed his fellowship training in Clinical Chemistry at Johns Hopkins. He currently serves as the Director of Main Chemistry within the Johns Hopkins Hospital Core Laboratories, as well as the Clinical Pharmacology Analytical Laboratory within the Division of Clinical Pharmacology. Dr. Marzinke also serves as the leader of the Clinical Laboratory Core for the Johns Hopkins Center for AIDS Research. His primary research interests are in the areas of antiretroviral pharmacology, HIV prevention science, pharmacogenetics, mass spectrometry, and laboratory automation. Dr Marzinke has an active research program and serves as a Principal Investigator (PI) or co-Investigator on several grants. He has collaborated on research to better characterize the multi-compartment pharmacology of antiretroviral agents when administered using alternative drug delivery systems. He has published more than 175 peer-reviewed articles, and holds leadership positions in several societies. View Dr. Marzinke’s Full Profile >>

Claire Knezevic, Ph.D.

Dr. Claire Knezevic is an Assistant Professor in the Johns Hopkins University School of Medicine, and serves as the Director of Critical Care Laboratories, Pre-Analytical Testing, and as Co-Director of the Drug Assay Laboratory. Dr. Knezevic obtained her undergraduate degree in chemistry from Scripps College and earned her PhD in organic chemistry from the University of Illinois at Urbana-Champaign. After conducting post-doctoral research in chemical proteomics at the Moffitt Cancer Center in Tampa, Florida, she then completed a COMACC-accredited clinical chemistry fellowship at the Johns Hopkins University School of Medicine. Dr. Knezevic is board certified in clinical chemistry by the American Board of Clinical Chemistry (ABCC) and the National Registry of Certified Chemists (NRCC), and is a Fellow of the AACC Academy. Dr. Knezevic has served as the President of the NRCC and currently serves as the Chair of the AACC Capital Section. Dr. Knezevic is the Assistant Director of the Clinical Pharmacology Analytical Laboratory, which performs quantitative LC-MS/MS assays of anti-infective drugs from a variety of biological matrices in support of clinical trials. Her research interests include therapeutic drug monitoring, pharmacogenetics, drug-drug interactions, and critical care testing.

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