Selected Publications

For a complete list please go to:

  1. Robin Welsh, Nianbin Song, and Sadegh-Nasseri. What to do with HLA-DO/H-2O two decades later? Immunogenetics. 2019 Jan 26. doi: 10.1007/s00251-018-01097-3. Review. PMID:30683973
  2. Sadegh-Nasseri, S. and AeRyon Kim. Selection of Immunodominant Epitopes During Antigen Processing is Hierarchical. Molecular Immunology. doi: 1016/j.molimm.2018.08.011  Review. PMID: 30146122
  3. Kim A, Boronina TN, Cole RN, Darrah E, Sadegh-Nasseri S. Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing. Scientific Reports. 2017 Apr 19;7:46418. doi: 10.1038/srep46418. PMID: 28422163
  4. Darrah E, Kim A, Zhang X, Boronina T, Cole RN, Fava A, Giles JT, Bingham III CO, Chalmers MJ, Griffin PR, Sadegh-Nasseri S, Rosen A. Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis. J Proteome Research. 2017 Jan 6;16(1):355-365. doi: 10.1021/acs.jproteome.6b00617. PMID: 27700100
  5. Sadegh-Nasseri S. A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells. F1000Res. 2016 Jun 9;5. pii: F1000 Faculty Rev-1305. doi: 10.12688/f1000research.7664.1. eCollection 2016. Review. PMID: 27347387
  6. Sadegh-Nasseri S, Kim A. MHC Class II Auto-Antigen Presentation is Unconventional. Frontiers in Immunology 2015 Jul 22;6:372. doi: 10.3389/fimmu.2015.00372. PMID: 26257739
  7. Kim A, Sadegh-Nasseri S. Determinants of immunodominance for CD4 T cells. Current Opinion in Immunology. 2015 Jun;34:9-15. doi: 10.1016/j.coi.2014.12.005. PMID: 25576665
  8. Kim A, Hartman IZ, Poore B, Boronina T, Cole R, Song N, Ciudad MT, Jaraquemada D, Sadegh-Nasseri S. Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources. Nature Communications. 2014 Nov 21;5:5369. doi: 10.1038/ncomms6369. PMID: 25413013

    F1000 recommendation Dec 3, 2014

  9. Poluektov YO, Kim A, Hartman IZ, Sadegh-Nasseri S. HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation. PLoS One. 2013 Aug 8;8(8):e71228. doi: 10.1371/journal.pone.0071228. eCollection 2013. PMID: 23951115
  10. Dalai, S. K., S. Khoruzhenko, C. G. Drake, C. C. Jie, and S. Sadegh-Nasseri. 2011. Resolution of Infection Promotes a State of Dormancy and Long Survival of CD4 Memory T Cells. Immunology and Cell Biology (NPG) 89: 870–881. PMID: 21358746
  11. Hartman, Isamu Z.*, AeRyon Kim*, Robert J. Cotter, Kimberly Walter, Sarat K. Dalai, Tatiana Boronina, David E. Lanar, Urszula Krzych, Robert N. Cole, and S. Sadegh-Nasseri. 2010. A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes. Nature Medicine 16:1333–1340. PMID 21037588.  Featured in JHMI Research Releases in October 31, 2010  “SHAPELY” GERMS SHAPE UP THE IMMUNE SYSTEM

           Also, in Nov 8, 2010 issue of JHU Gazette;

  12. Chou CL, Mirshahidi S, Su KW, Kim A, Narayan K, Khoruzhenko S, Xu M, Sadegh-Nasseri S. Short peptide sequences mimic hla-dm functions. Molecular Immunology 2008;45(7):1935-43.

           Faculty of 1000 Biology: evaluations for Chou CL et al Mol Immunol 2007 Dec 1:

  13. Narayan K, C-L Chou, A Kim, I Hartman, S Dalai and S. Sadegh-Nasseri. 2007. HLA-DM targets the hydrogen bond between the histidine at position 81 and peptide to dissociate HLA-DR–peptide complexes. Nature Immunology 8:92-100. PMID 17143275.

           Faculty of 1000 Biology: evaluations for Narayan K et al Nat Immunology 2007 Jan 8  (1):92-100, it received a “MUST READ” (8 points) evaluation

  14. Dalai SK, S Mirshahidi, A Morrot, F Zavala and S. Sadegh-Nasseri. 2008. Anergy in memory CD4+ T cells is induced by B cells.  Journal of Immunology 181(5):3221-31. PMID 18713993.
  15. Mirshahidi S, Korb Ferris L and S. Sadegh-Nasseri. 2004. The magnitude of TCR engagement is a critical predictor of T cell anergy or activation.  Journal of Immunology 172:5346-5355. PMID 15100274.
  16. Mirshahidi, Saied, Huang, Ching-Tai, S. Sadegh-Nasseri. 2001. Anergy in peripheral memory CD4+ T cells induced by low avidity engagement of T cell receptor. Journal of Experimental Medicine 194:719-732. PMID 11560989.
  17. Chou CL and S Sadegh-Nasseri. 2000. HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. Journal of Experimental Medicine 192:1697-1706 PMID 11120767.
  18. Natarajan SK, LJ Stern and S Sadegh-Nasseri.1999.SDS stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1.Journal of Immunology162:3463-70PMID 100928
  19. Natarajan SK, M Assadi and S Sadegh-Nasseri. 1999. Stable peptide binding to MHC class II molecules is rapid and is determined by a receptive conformation shaped by prior association of low affinity peptides. Journal of Immunology 162:4030-4036 PMID 10201925.
  20. Sadegh-Nasseri S & HM McConnell.1989. A kinetic intermediate in the reaction of an antigenic peptide and I-Ek. Nature 337:274-276 (PMID 2536141).
  21. Sadegh-Nasseri S and RN Germain.1991. A role for peptide in determining MHC class II structure. Nature 353:167-170 (PMID 1653903).
  22. Sadegh-Nasseri S, LJ Stern, DC. Wiley and RN Germain. 1994. Specific low affinity peptide binding precedes stable complex formation and preserves the function of MHC class II molecules. Nature 370: 647-650 (PMID 8065450).