Principal Investigator

Chuan-Hsiang Bear Huang, M.D., Ph.D.

Bear received an M.D. from National Taiwan University followed by two years of residency in internal medicine before arriving at Johns Hopkins University, where he obtained a Ph.D. in Immunology/Biophysics. In his thesis work, Bear determined the crystal structure of PI3Kα, one of the most frequently mutated proteins in human cancers. He went on to study the mechanism of cell migration as a Damon Runyon Fellow in the lab of Peter Devreotes. In 2016 Bear started his own lab in the Department of Pathology at Johns Hopkins where his team investigates signaling networks in tumorigenesis and how to target them for cancer treatment. In his free time Bear enjoys playing piano, fishkeeping, and astrophotography.

Research Associate

Jr-Ming Yang, Ph.D.

Ming received a B.S. in Computer Science and Information Engineering as well as an M.S. in Biochemical Sciences, both from National Taiwan University. She carried out her Ph.D. work on exosome biogenesis followed by a postdoctoral fellowship studying the function of the tumor suppressor gene PTEN at Johns Hopkins University. Ming is currently a research associate in the Department of Pathology. In her spare time, Ming enjoys gardening and taking care of pet guinea pigs.

Postdoctoral Fellow

Chao-Cheng (Jimmy) Chen, Ph.D.

  • B.S. National Yang-Ming University
  • Ph.D. National Yang-Ming University








Huiwang (David) Zhan, Ph.D.

  • B.S. Xiamen University
  • Ph.D. Johns Hopkins University



Graduate Student

Budri Abubaker-Sharif

  • B.S. Johns Hopkins University
  • MD, PhD Student
  • Graduate Program:  Biomedical Engineering


Undergraduate Student

Jessica Liang

• Biology, Johns Hopkins University










Gabriel Au

  • Biology, Johns Hopkins University

Suyang Wang

  • Chemical and Biomolecular Engineering, Johns Hopkins University


Wei-Yu (Jackie) Chi, M.D.

  • Current position: graduate student at Weill Medical College of Cornell University