Scientific Integration

Interactions and Collaborators

The Cervical Cancer SPORE is a highly interactive and multidisciplinary program incorporating four projects and three cores. Their interaction is pictured in the chart below. All projects are led by at least three investigators whose interest and knowledge span basic and clinical areas. In addition, investigators are frequently involved in more than one project, demonstrating the extent of collaborations between investigators across several project areas. Details of these intra-SPORE collaborations and interactions are detailed within each Project and Core. All projects take advantage of a single Biostatistics/Data Management Core (Core B) led by Drs. Chenguang Wang and Anne Rositch at JHU and Dr. Sejong Bae at UAB, all experienced biostatisticians with research interest in clinical trial design. The Tissue/Pathology/Immunology Core (Core C) is led by Dr. Russell Vang (JHU), a Pathologist, Dr. Raphael Viscidi, a Virologist specialized in the study of HPV, Dr. Todd Stevens (UAB), and Dr. Lawrence Lamb, an immunologist (UAB). Core C provides consistent specimen handling and analysis between Hopkins and UAB. Core C will also provide expertise for tissue-based immunological assays for Projects 2 and 3 of the SPORE program, which involve the acquisition of tissue samples from the trial patients. These common cores provide consistency and economy amongst the projects, and further foster collaboration within the program and between different institutions.