Carli was chosen for the P.E.O. Scholar Award based on her scholarly excellence, academic achievement, and career goals. Carli is studying the relationship between radiation exposure and radiotherapy and the gastrointestinal microbiome. She currently aspires to work for NASA and to study the effects of spaceflight on the human body, and particularly in the areas of immunology and the gut-brain axis.
New From Sfanos Lab: Differential Mast Cell Phenotypes in Benign versus Cancer Tissues and Prostate Cancer Oncologic Outcomes
Check out our new study published in Journal of Pathology examining mast cell subtypes in the prostate tumor microenvironment and in relation to prostate cancer oncologic outcomes!
New from Sfanos Lab: The Potential Effects of Radiation on the Gut-Brain Axis
As evidence for the interconnectedness between the gastrointestinal tract and the nervous system gains traction, Sfanos Lab graduate student Carli Jones reviews the potential effects of radiation (for cancer treatment and otherwise!) on the gut-brain axis. Check out the new review article here. Congratulations Carli!
New from Sfanos Lab: High Extra-tumoral Mast Cell Counts are Associated with a Higher Risk of Adverse Prostate Cancer Outcomes
Check out our latest report on the association between mast cell numbers at radical prostatectomy and outcomes in advanced prostate cancer. This study was led by former Sfanos Lab graduate student Dr. Heidi Hempel Sullivan. Congratulations Heidi!
New from Sfanos Lab: Interleukin-8 Expression is Associated with Prostate Cancer Aggressiveness and Androgen Receptor Loss in Primary and Metastatic Prostate Cancer
We recently published a study led by Dr. Janielle Maynard examining the overexpression of IL-8 in aggressive prostate cancer and in relation to androgen receptor loss in both primary and metastatic prostate cancer tissues. This pro-inflammatory cytokine is likely inhibited by the androgen receptor, and is expressed in both atrophic tissues and metastatic cancers where androgen receptor is downregulated or lost. Congratulations Janielle!
New from Sfanos Lab: Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis
Check out our new study led by former Pathobiology graduate student Dr. Corey Porter examining the silencing of the innate immune protein lactoferrin in PIN and prostate cancer. Dr. Porter is currently a postdoctoral fellow at the University of Michigan. Congratulations Corey!
Congratulations to Dr. Janielle Maynard for winning Translational Research Award!
Congratulations to postdoctoral fellow Dr. Janielle Maynard for winning the Honorable Ralph Burnett Poster Award for Translational Research at the 14th Annual Department of Urology Donald S. Coffey Ph.D. Prostate Research Day! Dr. Maynard’s poster was entitled “Targeting P2X4 Purinergic Receptors in Aggressive Prostate Cancer“. Fantastic work Janielle!
Summer in Sfanos lab
Congratulations to our summer students Xavier Aviles Hernandez as part of the CSM Summer Internship Program (SIP) and Mya Smith as part of the MERIT program on the successful completion and presentation of their summer research projects under the mentorship of postdoctoral fellow Dr. Janielle Maynard! Mya won 2nd place in her poster session in the high school category!
New from Sfanos Lab: A prospective study of the urinary and gastrointestinal microbiome in prepubertal males
We recently published a study led by Johns Hopkins Medical student Borna Kassiri that establishes the presence of a urinary microbiome in prepubertal males and looks at the effects of antibiotic use on the GI and urinary microbiome in the pediatric population. Congratulations Borna!
New from Sfanos Lab: Inflammation‐associated pathologies in a case of prostate schistosomiasis: Implications for a causal role in prostate carcinogenesis
Check out our latest study from Sfanos lab CMM graduate student/postdoctoral fellow Dr. Lauren Peiffer. Our study describes an unusual case of prostate schistosomiasis and potential implications for a role for this infection in aggressive prostate cancer.