Check out our new study that characterized the gastrointestinal microbiota as individuals with metastatic CRPC who are progressing on enzalutamide initiate treatment with pembrolizumab. The study, headed by former Sfanos Lab graduate student Dr. Lauren Peiffer was recently published in Neoplasia. Congratulations Lauren!
Congratulations to Carli Jones for being awarded a Johns Hopkins Pathology Young Investigators’ Day Translational Research Award for her work entitled “The microbial metabolite equol as a radiosensitizer and therapeutic agent in prostate cancer”. Strong work Carli!
Check out our recent publication in PNAS that identifies a potential relationship between bacterial infections and prostate cancer initiation. This study was championed by former Sfanos Lab graduate student Dr. Eva Shrestha. Congratulations Eva!
Congratulations to Sfanos lab undergraduate student Rebecca Sosa on being awarded the 3rd place Margaret Foti Foundation Undergraduate Prize for Cancer Research for her recent participation in the AACR Undergraduate Student Caucus and Poster Competition! Becca presented her research “Verification of Subclonal CDKN1B mRNA Loss in Primary Prostate Cancer Tissues using RNA in situ Hybridization”. Great work Becca!
Carli was chosen for the P.E.O. Scholar Award based on her scholarly excellence, academic achievement, and career goals. Carli is studying the relationship between radiation exposure and radiotherapy and the gastrointestinal microbiome. She currently aspires to work for NASA and to study the effects of spaceflight on the human body, and particularly in the areas of immunology and the gut-brain axis.
Check out our new study published in Journal of Pathology examining mast cell subtypes in the prostate tumor microenvironment and in relation to prostate cancer oncologic outcomes!
As evidence for the interconnectedness between the gastrointestinal tract and the nervous system gains traction, Sfanos Lab graduate student Carli Jones reviews the potential effects of radiation (for cancer treatment and otherwise!) on the gut-brain axis. Check out the new review article here. Congratulations Carli!
Check out our latest report on the association between mast cell numbers at radical prostatectomy and outcomes in advanced prostate cancer. This study was led by former Sfanos Lab graduate student Dr. Heidi Hempel Sullivan. Congratulations Heidi!
We recently published a study led by Dr. Janielle Maynard examining the overexpression of IL-8 in aggressive prostate cancer and in relation to androgen receptor loss in both primary and metastatic prostate cancer tissues. This pro-inflammatory cytokine is likely inhibited by the androgen receptor, and is expressed in both atrophic tissues and metastatic cancers where androgen receptor is downregulated or lost. Congratulations Janielle!
Check out our new study led by former Pathobiology graduate student Dr. Corey Porter examining the silencing of the innate immune protein lactoferrin in PIN and prostate cancer. Dr. Porter is currently a postdoctoral fellow at the University of Michigan. Congratulations Corey!
