Current Lab Members

Faculty

 

charles3-1Charles G. Eberhart, M.D., Ph.D. (Professor; Pathology, Ophthalmology and Oncology; Director; Division of Neuropathology) studied meiotic cell cycle regulation in Drosophila spermatogenesis during his graduate studies at the University of Texas Southwestern Medical School in Dallas. After completing his MD and PhD degrees, he trained in Anatomical Pathology and Neuropathology at Johns Hopkins. He started his own laboratory in 2001.

 

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Fausto J. Rodriguez, M.D. (Assistant Professor; Pathology and Oncology). Dr. Rodriguez received his undergraduate and M.D. degrees from the University of Missouri-Columbia. After graduating he pursued anatomic pathology residency, neuropathology fellowship and neuro-oncology research fellowship at Mayo Clinic, Rochester, Minnesota. He remained as faculty at Mayo for two years prior to assuming his current position at Hopkins. Currently he is an assistant professor of Pathology and Oncology. Dr. Rodriguez work aims to identify diagnostic, prognostic, and therapeutic biomarkers in primary brain tumors. His current research efforts specifically focus on the study of signaling pathways, such as MAPK and mTOR, and microRNA regulation in the biology of pediatric gliomas.

 

Eric H. Raabe M.D., Ph.D. (Assistant Professor, Pediatric Oncology and Pathology). Dr. Raabe completed MD and PhD studies at the University of Cincinnati College of Medicine, pediatrics residency at the Children’s Hospital of Philadelphia, and pediatric hematology/oncology fellowship at Johns Hopkins. He joined the Eberhart laboratory at a research fellow in July 2008 during his fellowship. Dr. Raabe was promoted to Instructor on the Oncology Department Faculty in July 2011 and Assistant professor in 2012. He uses human neural stem cells to create gain of function models of aggressive pediatric brain tumors. Dr. Raabe also uses cell lines derived from patients to test new drugs to help children with brain tumors. Dr. Raabe is a St. Baldrick’s Scholar: (http://www.stbaldricks.org/.)

 

lauraLaura Asnaghi Ph.D. (Research Associate) received her Ph.D. in 2002 from the Dept. of Pharmacology at the University of Milan (Italy). She subsequently worked as postdoctoral fellow in the Laboratory of Cellular Oncology directed by Dr. Douglas Lowy (National Cancer Institute, NIH, Bethesda, MD, USA). She began working in the Eberhart Lab in fall 2008, and was promoted to Research Associate in fall 2011. Her projects are mainly focused on ocular oncology (uveal melanoma, ocular surface squamous neoplasia, retinoblastoma).

 

MingMing Yuan Ph.D. (Research Associate) Dr.Yuan received her Ph.D. from the Umea University, Sweden. She worked as postdoctoral fellow in the Dept. of Radiation Oncology and Molecular Radiation Sciences at Johns Hopkins University. She performed RNAi screening to identified novel tumor suppressor for glioblastoma. She joined the Eberhart, Rodriguez and Raabe laboratory in July 2014. Her current project focuses on low grade pediatric glioma.

Fellows

 

harpreetHarpreet Kaur Ph.D. (post-doctoral fellow). Dr. Kaur received her PhD from The University of Toledo in Ohio. Her doctoral studies focussed on cell cycle regulation in cancer. She investigated the role of cell adhesion proteins in GBM during her three years of postdoctoral research at Case Western Reserve University, Ohio. She joined the Eberhart and Raabe laboratory in May 2012. Her current projects focus on the role of stem cell factors, specifically HMGA proteins, in adult and pediatric brain tumors. 

 

jeffrey Jeffrey Rubens M.D. (clinical-research fellow). Dr. Rubens is a pediatric hematology-oncology clinical and research fellow at Johns Hopkins Hospital. Dr. Rubens’ project focuses on LIN-28 in atypical rhabdoid tumors of the brain to help understand the malignant transformation of normal brain tissue and to help find curative therapeutics for this deadly tumor.

 

 

antje

Antje Arnold Ph.D. (post-doctoral fellow). Dr. Arnold received her PhD from the University of Jena, Germany. Her doctoral studies focused on the derivation of human IPS cells with mRNA transfection. In her postdoctoral research at the Johns Hopkins University, Department of Radiology, she investigated the myelination status of primary human glial restricted progenitors cells after transplantation into myelin deficient mice with MRI. Dr. Arnold joined the Eberhart, Rodriguez and Raabe laboratory in August 2016. Her current projects focus on low- and high-grade gliomas.

Graduate Students

 

SamSamantha Semenkow is a graduate student in the Pathobiology program and has a BS in Molecular Biology, Biochemistry, and Bioinformatics from Towson University.  Her research focuses on how the Notch pathway and epigenetic mechanisms contribute to pathogenesis of adult Glioblastoma.

 

 

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Allison Hanaford is a graduate student in the Pathobiology Program and has a BS in Biology from California State University. Her research focuses on developing therapeutic strategies for treating medulloblastoma, the most common malignant pediatric brain tumor.

 

 

 

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Brad Poore is a graduate student in the Pathobiology Program who received his BS in Cell Biology and Neuroscience from Montana State University. His research focuses on examining the metabolic and phenotypic differences of Lin28A and Lin28B overexpression in gliomas, as well as the effect of glutaminase inhibitors on MYC driven cancers.

 

 

Research Technicians

 

Anne Price has worked in the Neuropathology Division for over 15 years, predominantly in the laboratory of Dr. Lee Martin. She joined the Eberhart group in spring 2011.

 

 

 

 

Rotating Students

 

OrlandiOrlandi Valencia Novak joined the lab in summer 2014 and works with Dr. Raabe on pediatric brain tumors.

 

 

 

 

photoRachel Elizabeth Maynard joined the lab in Summer 2014 and works with Dr. Raabe on pediatric diffuse intrinsic pontine glioma.

 

 

 

 

holly

Holly Guo is an undergraduate student at The Johns Hopkins University studying Biomedical Engineering. She joined the lab in fall 2015 and works with Dr. Kaur on the role of stem cell factor Lin28B and HMGA2 in regulating Diffuse Intrinsic Pontine Glioma cell proliferation and apoptosis.

 

 

sabrina

Sabrina Wang is an undergraduate Neuroscience major, graduating in May 2018 from The Johns Hopkins University. She joined the lab in the spring of 2016, and is working with Jeff Rubens investigating the potential therapeutics of DON in atypical teratoid rhabdoid brain tumours.

 

 

alara

Alara Hector is a highschool senior at Arundel Highschool, who is planning to major in biology in the following years. Currently, she his interested in examining possible synergistic combinations between MEK and MTORC inhibitors with standard based chemotherapy treatments for low grade gliomas.

 

wonjoongWonjoong Richard Kim is an undergraduate student at The Johns Hopkins University and  joined the lab in September 2016. He works with Dr. Arnold on pediatric low-grade brain tumor.